PMID: 35224210 Activation of regulatory T cells triggers specific changes in glycosylation associated with Siglec-1-dependent inflammatory responses

[Mindyporterfield]

T-Cell-210Paper

[Mindyporterfield]

• [x] Mindy- read paper, id data to be curated (which figures etc), draw an example structure paying attention to reducing end type (free or reduced) and modifications (permethylation). Write a ticket for Anh and link example structure.

• [x] Anh-Draw assigned structures using GRITS, export as gws file and put in the corresponding folder in sharepoint, comment in github to let me know its done.

• [ ] Mindy-check structures, give any needed feedback

Mindy -proceed with the rest of the curation workflow

• [ ] -convert structures (Sena) and get glytoucan ids

• [ ] -verify structures match glytoucan structure

• [ ] -Fill in remaining info for species, etc https://docs.google.com/document/d/1QPWU29l6pzo8bKIQ6epEidPDDxyp-5JQk9drhS-zJOg/edit#heading=h.urs6nll5b27n

• [ ] -deposit in sharepoint and comment on ticket

[Mindyporterfield]

Please draw structures from figure 4, N glycans, free, permethylated, Na 2 sets, Activate and resting

[apnguyen98]

Please find the drawn structures for this paper in the folder: https://gwu0.sharepoint.com/sites/GlyGenTeam-GRP/Shared%20Documents/Forms/AllItems.aspx?csf=1&web=1&e=RJR8nh&cid=908f3b6d%2D4a53%2D4132%2Db222%2Dee26ac5da57e&FolderCTID=0x01200081407FA815A7124E846BD764353D93CC&id=%2Fsites%2FGlyGenTeam%2DGRP%2FShared%20Documents%2FPaper%20Curation%2FPMID%C2%A035224210%20T%2DReg%2FGWS&viewid=6ffb8fed%2D81e7%2D4af7%2Dbfcd%2Da6f29c268132

Activate and Resting sets both have the same exact structures and masses so I only did it once, but let me know if I sould duplicate the files