PMID: 31889402 Glycan biomarkers for Alzheimer disease correlate with T-tau and P-tau in cerebrospinal fluid in subjective cognitive impairment

[Mindyporterfield]

AlzFolder

[Mindyporterfield]

• [x] Mindy- read paper, id data to be curated (which figures etc), draw an example structure paying attention to reducing end type (free or reduced) and modifications (permethylation). Write a ticket for Anh and link example structure.

• [x] Anh- Draw assigned structures using GRITS, export as gws file and put in the corresponding folder in sharepoint, comment in github to let me know its done. @apnguyen98

> - [ ] Supplemental Figure 1 A control
> - [ ] Supplemental Figure 1 B MCU
> - [ ] Supplemental Figure 1 C AD 
> - [ ] Supplemental Figure 2 A control
> - [ ] Supplemental Figure 2 B likely AD
> - [ ] Supplemental Figure 2 C definitive AD

- [ ] Mindy-check structures, give any needed feedback

@senaarpinar 
- [ ]     -convert structures in the GWS folder (Sena) and get glytoucan ids, put excel in same folder

Mindy -proceed with the rest of the curation workflow

- [ ]     -verify structures match glytoucan structure

- [ ]     -Fill in remaining info for species, etc [https://docs.google.com/document/d/1QPWU29l6pzo8bKIQ6epEidPDDxyp-5JQk9drhS-zJOg/edit#heading=h.urs6nll5b27n](https://github.com/orgs/glygener/projects/7/views/url)

- [ ]     -deposit in sharepoint and comment on ticket

[apnguyen98]

@Mindyporterfield Please check the finished Glycan structures here! https://gwu0.sharepoint.com/sites/GlyGenTeam-GRP/Shared%20Documents/Forms/AllItems.aspx?id=%2Fsites%2FGlyGenTeam%2DGRP%2FShared%20Documents%2FPaper%20Curation%2FPMID%C2%A031889402%2DAlz%2FGWS&viewid=6ffb8fed%2D81e7%2D4af7%2Dbfcd%2Da6f29c268132

[senaarpinar]

@Mindyporterfield I generated the excel file with the glytoucanids.

[senaarpinar]

uploaded a new version of the excel file (after rerunning with Rene's changes to handle structures with brackets)

[Mindyporterfield]

@senaarpinar can you re run the GWS files to get the new format incorporated. Also please keep the files separate rather than combining them. Thank you

[senaarpinar]

@Mindyporterfield I reran and uploaded the separate files. Please have a look and let me know if you need anything different