gmhhope
commented
1 year ago In a lot of the papers we looked at they use EBV or CMV to see how the reactions may differ. Do they do this because these are viruses that can lie dormant? What are the other reasons for doing this? Seeing that COVID is a respiratory virus while CMV and EBV infect immune cells?
CMV and EBV especially EBV has been known to associate with PASC symptoms (e.g., fatigue, flu-like symptoms). This can be learned from ME/CFS patients of which a significant portion has history of Epstein-Barr Virus and Infectious Mononucleosis. Another one is the history of Lym disease also characterized by fatigue, cognitive symptoms.
Discussion worksheet
The paper you are working on?
Su, Y. et al. Multiple early factors anticipate post-acute COVID-19 sequelae. Cell 185, 881- 895.e20 (2022).
Main Research Question, Contribution to the fields?
Researchers of this paper investigate multi-factors that may contribute to long covid.
Methods & Data
Authors' interpretation
I agree with the authors interpretation, I think they did a great job using cohorts from different groups.
Enhancement or next experiment?
I would be interested to see how vaccination may play a role in long covid symptoms. On the CoronaPod they said that some people got relief from vaccinations while some people had break through cases where they were vaccinated and still got COVID and long covid.
Confusion? Terms you don't understand?
In a lot of the papers we looked at they use EBV or CMV to see how the reactions may differ. Do they do this because these are viruses that can lie dormant? What are the other reasons for doing this? Seeing that COVID is a respiratory virus while CMV and EBV infect immune cells?
Have your own opinions or critiques
I hereby confirm that I have: