greenelab / BioBombe

BioBombe: Sequentially compressed gene expression features enhances biological signatures
https://greenelab.github.io/BioBombe/
BSD 3-Clause "New" or "Revised" License
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Adding Unequal Variance to Signature Analysis T-Test #186

Closed gwaybio closed 5 years ago

gwaybio commented 5 years ago

ef98d58511a0750fc050d1af55f377e9dd4770ff is the major change of this pull request.

I tracked this error down after failing to align t-test results in subpanels b, d, and f to the results shown in a, c, and e (respectively).

A t-test with equal variance assumption will fail to identify cases found in b.

Another minor change is plotting panels b and d with the test-set features only. Previously, panels a and b were calculated using the test set and panels b and d were generated using the training set. Now, b and d use the test set.

I reran the pipeline after these changes and all files here are updated.

Updated Figure

full_separation_plot