Introduce yourself here first!

[cgreene]

Hello interested contributors! Welcome to the covid19-review project. Our goal here is to provide an up-to-date perspective on the current peer reviewed and preprinted literature around diagnostics and therapeutics relevant to COVID-19. There's more in our README, which you may have already seen: https://github.com/greenelab/covid19-review#sars-cov-2-and-covid-19-an-evolving-review-of-diagnostics-and-therapeutics

As a first step, let's get to know each other. Please answer these questions!

• Your name
• Your job other than this review
• What you hope to get out of participating
• How you feel best prepared to contribute
• What you have the most trepidation about

[cgreene]

• Your name: Casey Greene
• Your job other than this review: When I'm not doing this, I mentor folks in a computational biology lab at UPenn and help Alex's Lemonade Stand Foundation with their Childhood Cancer Data Lab
• What you hope to get out of participating: It has become increasingly clear that diagnostics and therapeutics will have key roles to play in addressing COVID-19. I'm interested in learning more about what's being evaluated and what stage it's at. I'm excited about the rapid sharing, especially on twitter and social media, but I'm concerned that a lot of nuance is being lost.
• How you feel best prepared to contribute: This will be my second massively open online review paper that I've worked on. I'm happy to review text, read some papers, and contribute in whatever way I can.
• What you have the most trepidation about: I was a PhD student in a Molecular and Cellular Biology program a while ago and have some experience reading such papers from journal club, but it's been a while. I'm excited and nervous about getting back into that literature.

[averyposey]

Your name: Avery Posey
Your job other than this review: Assistant Prof @ UPenn, CAR-T cell engineering for cancer as well as pro-inflammatory diseases
What you hope to get out of participating: I want to contribute to distilling the large body of work in this rapidly evolving area.
How you feel best prepared to contribute: I want to read papers that have assessed immune-related components of COVID-19.
What you have the most trepidation about: This is my first massive open online review and I am interested to see how this goes.

[mprobson]

• Your Name: Michael Robson
• Your job other than this review: Assistant Professor of Computer Science at Villanova University
• What you hope to get out of participating: Make a meaningful contribution to a high-impact project that will help in the ongoing crisis (by making it easier for scientists and others to contribute)
• How you feel best prepared to contribute: Software, git tutorials, GitHub maintenance, general non-biology but technical expertise
• What you have the most trepidation about: I know very little helpful biology

[KhiabanianLab]

– Your name: Hossein Khiabanian – Your job other than this review: Assistant Professor at Rutgers (computational biology, cancer genomics) – What you hope to get out of participating: Small contribution to a large review (my first) of literature as we learn more about this coronavirus and the pandemic it has caused. – How you feel best prepared to contribute: I have previously worked on molecular epidemiology of influenza and ebola using simple statistical models. – What you have the most trepidation about: I am very interested in modes of transmission and their relationship with the viral load given the wide spectrum of symptoms and severity during the infection.

[LucyMcGowan]

This is great, just saw your post in NPIS.

• Lucy D’Agostino McGowan
• Assistant Professor in Statistics, Wake Forest University
• I’ve been trying to synthesize the medical literature for my friends / family - Would be great to have lots of minds on this (and be able to contribute as well!)
• My PhD & postdoc were in biostatistics & I have a lot of GitHub experience - happy to contribute both to the stats & organization
• I’m currently committed to a lot of projects, but this is important - biggest trepidation is just finding time for everything

[luispedro]

Your name: Luis Pedro Coelho

Your job other than this review: Junior Principal Investigator in computational biology, Fudan University

What you hope to get out of participating: I hope to learn more myself most of all

How you feel best prepared to contribute: I am switching some of my time to Covid-19 related work starting this week, so I will be reading a lot in the very near future

What you have the most trepidation about: this is a bit far from my main area of expertise, although I put some of that on hold given the state of emergency

[SiminaB]

Thank you for starting this Casey!

• Simina Boca
• Faculty at the Innovation Center for Biomedical Informatics and Oncology & Biostatistics at Georgetown
• Help with a relevant and timely project! Also, I had a ton of fun with the collaborative deep review, and some fun is sorely needed right now
• Statistical and study design issues, systematizing results. My background is in biostats and I've taught evidence-based data analysis to med and grad students
• Finding the time to keep on top of everything, especially since I know many preprints are coming out daily

[abreddy8]

• Your name: Akhilesh Reddy
• Your job other than this review: When I'm not doing this, I lead a research group at Penn focused on the molecular biology of circadian (24 hour) clocks and sleep.
• What you hope to get out of participating: Some proper fact-based insights into the emerging literature in this field.
• How you feel best prepared to contribute: I am a clinician-scientist (MD-PhD) with a broad interest, and my lab has previously investigated the interactions between virus and host in the context of the circadian cycle. I should be able to provide a discerning eye for the clinical aspects, as well as the basic science. I'm happy to review text, read some papers, and contribute in whatever way I can.
• What you have the most trepidation about: Juggling lots of new COVID projects working virtually.

[cbrueffer]

• Your name: Christian Brueffer

• Your job other than this review: Bioinformatician at SAGA Diagnostics working on cancer molecular diagnostics, and PhD student in cancer genomics at Lund University.

• What you hope to get out of participating: Learning more about virology, particularly in the SARS-CoV-19 context, and getting experience in writing reviews.

• How you feel best prepared to contribute Experience with (non-virology) scientific literature, programming, data analysis/visualization, GitHub, and reviewing/writing/editing text.

• What you have the most trepidation about: Keeping on top of literature outside my area of expertise while my normal obligations continue.

[nilswellhausen]

Your name: Nils Wellhausen

Your job other than this review: Being a Pharmacology Graduate student. Learning computational biology, keeping up with the literature in general and playing guitar.

What you hope to get out of participating: Learning more about the current approaches to tackle this global issue but also being able to expand my knowledge and help writing a comprehensive review informing the community.

How you feel best prepared to contribute: We started a COVID 19 journal club in the wherry lab so I have been relatively up to date with the literature. I also worked with the high throughput screening core around David Schultz that is currently screening drugs for COVID-19.

What you have the most trepidation about: Being able to critically evaluate all the preprints coming out and of course keeping up with all commitments.

[agitter]

• Your name: Anthony Gitter
• Your job other than this review: I lead a computational biology research group at the University of Wisconsin-Madison and the Morgridge Institute for Research
• What you hope to get out of participating: This is a perfect use case for Manubot, and I want the review to thrive; I also want to better educate myself about COVID-19
• How you feel best prepared to contribute: I have experience with Manubot and collaborative reviews so I'd like to help domain experts become comfortable with this nontraditional writing process
• What you have the most trepidation about: This a fast-moving, high-stakes area; it will be difficult but imperative to summarize the literature accurately and review contributions thoroughly

[juliettemarie0405]

Your name: Juliette Rando

Your job other than this review: I'm a research specialist in a virology lab (studying HIV/SIV) at the Perelman School of Medicine at UPenn and an MPH candidate.

What you hope to get out of participating: I want to help in this time of crisis in any way possible.

How you feel best prepared to contribute: I'm ready and willing to put time into sifting through the literature. I have experience conducting a systematic review in the past.

What you have the most trepidation about: My virology knowledge is HIV-focused, and I do not have an advanced degree in biology. So I will definitely be deferring to the experts in this project!

[rays1987]

• Your name: Sandipan Ray (Ph.D., MRSB) • Your job other than this review: I am a senior post-doctoral fellow at the Department of Systems Pharmacology & Translational Therapeutics, Perelman School of Medicine, University of Pennsylvania • What you hope to get out of participating: Getting more information regarding this new SARS-CoV-2 infection. Bringing the essential information regarding this novel infection from the published and pre-print literature • How you feel best prepared to contribute: I have considerable expertise in cutting-edge proteomics (and systems biology) for studying infectious diseases (including dengue fever, malaria and leptospirosis). I have experience of writing systematic reviews in the past. Systems level approaches (including transcriptomics, proteomics and metabolomics) can provide extremely useful information regarding coronavirus 2 infection and may help in identifying effective early diagnostic and therapeutic (for both drugs and vaccines) targets. In this vein, the full-length genome sequences of nCoV-2019 and the phylogenetic analysis of the complete viral genome are published very recently (Wu et al., Nature 2020, PMID: 32015508; Lu et al., Lancet. 2020, PMID: 32007145, and Zhou et al., 2020, PMID: 32015507), while the proteome level studies are on their way (https://www.researchsquare.com/article/rs-17218/v1). I would like to contribute in a section on how systems approaches are proving new mechanistic insights into the pathogenesis of nCoV-2019 and host responses towards this infection. Additionally, I will be happy to review the other sections of manuscript. • What you have the most trepidation about: Trying to be familiar with the current trends of this novel pathogenic SARS-coronavirus 2 while working virtually.

[rmrussell]

Your name: Ronnie Russell

Your job other than this review: PhD student at the University of Pennsylvania studying HIV and SIV

What you hope to get out of participating: I hope to gain a more comprehensive understanding of coronaviruses (SARS-CoV-2 + the many others waiting to emerge!) and utilize my current knowledge of viruses in a useful way

How you feel best prepared to contribute: Part of my thesis work is studying cross-species transmission of primate lentiviruses (HIV and SIV), specifically barriers to these events (ie host receptor diversity) and viral adaptations following successful zoonoses. As SARS-CoV-2 is a zoonotic virus, a lot of basic biology lessons we have learned over the years for SIV/HIV should be directly translatable.

What you have the most trepidation about: My background on coronavirus biology is limited and papers are being published so quickly that trying to distill the accurate, peer-reviewed information from the deluge of preprints is like (as they say) trying to drink from a firehose.

[gregszetoAI]

• Your name: Greg Szeto
• Your job other than this review: about to be former TT assistant professor at UMBC. Just started my role as PI/Assistant Investigator at the Allen Institute for Immunology. I lead trainees and teams to do a lot of immunology (systems and molecular) and immunoengineering across healthy organisms and in diverse diseases, most recently cancer immunology and immunotherapy, lupus, and traumatic brain injury.
• What you hope to get out of participating: Contributing to a critical assessment of the literature, with hopefully some idea generation about host factors that may be contributing to the many differences in SARS-CoV2 vs. recent emergent coronaviruses. This also seems like a great time to refresh my domain knowledge in virology. How you feel best prepared to contribute: I TA'd Hopkins SPH Virology for multiple years and did my PhD in HIV latency, so I feel confident in interpreting critical readings of the literature on viral pathogenesis and drug development. I also have a solid footing in bioinformatics to help contribute to sections on -omics studies.
• What you have the most trepidation about: I have never done a fully crowd-sourced review. The rate of publications and data release has my head spinning. I am also concerned about the broader impacts of ongoing and upcoming control measures on society.

[Huiyanangelchow]

Your name: Huiyanangel(Angel) Chow Your job other than this review: I am a research specialist in Dr. Carl June lab at the Perelman School of Medicine at the University of Pennsylvania. What you hope to get out of participating: 1) trace the animal origin of COVID-19, 2) invalidate some rumors and disinformation about COVID-19, 3) know more about testing, metastasis, a model of this global epidemic, role of the environment in this crisis How you feel best prepared to contribute: while I compare this outbreak with SARS in hongkong, I will look at factors that make this outbreak deviated from the SARS crisis.
What you have the most trepidation about: not being able to sleep well and think clearly

[rando2]

Your name: Halie Rando Your job other than this review: I'm a new post-doc at UPenn working with Casey Green (@cgreene). I'm a computational biologist and typically work on animal models of complex diseases, but right now I am here almost full-time to answer questions, provide technical support, and open discussions for different topics related to this review. What you hope to get out of participating: I'm excited to be part of a multi-disciplinary effort that will allow us to use our collective interest in this topic and varied skill sets to make a real difference during a stressful time How you feel best prepared to contribute: I am helping run the technical side of things, recruiting subject area experts, and trying to make this project as user friendly as possible. I also love to write and edit! What you have the most trepidation about: I don't have much virology background -- if you want a three-minute distraction, these experimentally bred foxes were the subject of my genomics-focused PhD

[orpanag]

• Name: Orestis Panagiotou
• Job other than this review: Epidemiologist and Health Services Researcher; Assistant Professor, Brown University SPH
• What I hope to get out of participating: I am just glad to join this effort
• How you feel best prepared to contribute: I have expertise in evidence synthesis, meta-analysis, bias assessments, clinical epidemiology, and evidence-based medicine. Among other things, I conduct systematic reviews for AHRQ
• What you have the most trepidation about: There are many components in this project, ranging from basic science (e.g. viral genome sequencing) to treatment (e.g. comparing drugs) to decision analysis (e.g. decisions need to be made based on limited evidence but we don't have the luxury of waiting for RCTs).

[shrutir]

• Your name: Shruti Rao
• Your job other than this review: Research Instructor at the Innovation Center for Biomedical Informatics and Dept of Oncology at Georgetown University
• What you hope to get out of participating: I am excited to be part of this crowdsourcing effort to write a such a timely review paper.
• How you feel best prepared to contribute: I have a background in molecular biology and primarily work as a biocurator on research projects, which involves extracting, organizing and standardizing information from scientific literature and presenting them in databases. Happy to critically evaluate literature on COVID-19 and summarize information for the manuscript.
• What you have the most trepidation about: Finding the time to keep up with emerging literature on this topic while simultaneously refreshing my virology and immunology knowledge. 

[soumitagh]

Your name: Soumita Ghosh Your job other than this review: Research Associate in Dr. Garret Fitgzerald lab, University of Pennsylvania. What you hope to get out of participating: It is timely to focus on a problem that affected the world with my current expertise. It is important to combine knowledge as well as misconception that is presently going on. T How you feel best prepared to contribute: I am working in a lab where NSAIDs and prostaglandins are important topic for research. Previously I worked in malaria hence I read about chloroquine. I would like to focus on different drugs that has been suggested to soIve the crisis. What you have the most trepidation about: I donot have much of virology background.

[eberwine]

Your name: Jim Eberwine Your job other than this review: Professor of Systems Pharmacology and Translational Therapeutics What you hope to get out of participating: Better understanding of COVID-19 biology How you feel best prepared to contribute: I am a genomicist, neuroscientist, molecular biologist and hope the this expertise will be useful in understanding aspects of the viruses biology What you have the most trepidation about: I hope that the literature is filled with good quality data but I worry that the data may not be as good as we want and need.

[rdvelazquez]

Your name: Ryan Velazquez Your job other than this review: Data Scientist at Azimuth1 What you hope to get out of participating: Learn more about COVID-19 and help in any way needed How you feel best prepared to contribute: Help people with domain knowledge who aren't familiar with GitHub or Manubot.

[aadattoli]

Your name: Anna Ada Dattoli Your job other than this review: Postdoc in the Eberwine lab (system pharmacology and translational therapeutics) at UPenn What you hope to get out of participating:make a substancial contribution to help the ongoing crisis How you feel best prepared to contribute: molecular biology and data analysis expert. What you have the most trepidation about: critical analysis of the data.

[rhagenson]

• Your name: Ryan A. Hagenson
• Your job other than this review: Bioinformatics Scientist (and HPC SysAdmin) at Omaha's Henry Doorly Zoo and Aquarium
• What you hope to get out of participating: Enable the growth and legitimization of large-scale open collaborations
• How you feel best prepared to contribute: Most of my training and career thus far has been enabling non-computational biologists to learn and utilize computational resources effectively. Beyond that I focus on taking "slow" analysis and making it "fast" via ample use of concurrency, HPC, and reproducible elements.
• What you have the most trepidation about: Literature in this collab being misinterpreted by the most willing or most available rather than the most fit to review and understand it.

[mikemitchellupenn]

Your name: Mike Mitchell Your job other than this review: Assistant Professor of Bioengineering @ UPenn; Drug delivery, nucleic acid therapeutics What you hope to get out of participating: Better understanding of COVID-19 treatments How you feel best prepared to contribute: My collaborator Drew Weissman (UPenn) and I have significant interests in the design and implementation of mRNA vaccines, and are following COVID-19 mRNA vaccine research closely. Would be happy to review this literature if needed. What you have the most trepidation about: Never done a crowd-sourced review

[rbharath]

Thanks for starting this effort!

Your name: Bharath Ramsundar Your job other than this review: Entrepreneur. Lead developer of the DeepChem project. What you hope to get out of participating: Help build understanding of Covid19 among the scientific community How you feel best prepared to contribute: I've been maintaining a running list of summaries/commentaries on interesting preprints/papers at https://forum.deepchem.io/t/interesting-preprints-papers-on-coronavirus/99. I'd be glad to add some of these references to the manuscript What you have the most trepidation about: I'm not an expert at virology/immunology and want to be careful not to misrepresent something.

[aadattoli]

Dear Casey,

Here I upload a document with several points of discussion, including the most recent literature on the most hopeful experimental drugs (I have found 4 of them), as well as diagnostic tests, based on antibody detection, recently developed. I also added some thoughts concerning the Italian Covid-19 situation.

Please let me know your feedback.

Best,

Ada 20200326_Corona virus review.pdf

[ivlachos]

Awesome Initiative! Your name: Ioannis Vlachos Your job other than this review: PI at HMS/BIDMC/Broad, and also run the non-coding RNA bioinformatics Unit at the HIRM non-coding RNA Core. What you hope to get out of participating: Become part of a community effort to create a useful resource for tackling COVID-19 How you feel best prepared to contribute: We are switching part of our research resources to COVID-19 and I'm following the relevant literature closely. What you have the most trepidation about: Juggling one more fast-paced project

[RLordan]

Great idea folks! Your name: Ronan Lordan Your job other than this review: Postdoctoral Researcher, Garret A. FitzGerald’s Lab at the University of Pennsylvania What you hope to get out of participating: Contribute whatever I can to consolidate and critique the current influx of papers appearing relating to therapeutics for coronavirus. How you feel best prepared to contribute: My previous background was on researching anti-inflammatory therapeutics and nutraceuticals. I want to critique the novel therapeutics being proposed in the literature. In particular, I am interested in a recent mini-review discussing potential nutraceuticals targeting RNA viruses as there is little clinical evidence in this research field. (https://www.sciencedirect.com/science/article/pii/S0033062020300372?via%3Dihub). What you have the most trepidation about: Making an impactful contribution with my limited virology knowledge and using github (a learning curve for me).

[a-r-j]

Your Name: Arian Jamasb You job other than this review: PhD student, Co-supervised by Tom Blundell & Pietro Lio at the University of Cambridge What you hope to get out of participating: I'd like to keep on top of the papers relating to structural biology & drug repurposing for COVID-19 How you feel best prepared to contribute: I am happy to write about structural biology and virtual screening campaigns relating to COVID-19 What you have the most trepidation about: I'm not a virologist & I've never written a review in this manner.

[adamlmaclean]

• Your name: Adam MacLean

• Your job other than this review: Assistant professor of quantitative and computational biology at USC. Our research group studies cell signaling, single-cell, and stem cell biology.

• What you hope to get out of participating: Better understanding of the Covid-19 literature; new methods for the fast and efficient critical evaluation of (large numbers of) papers, and ways to communicate findings to the public.

• How you feel best preparedness to contribute: I have worked on modeling population dynamics and statistical inference methods, including SIR models, hope to contribute to discussion and evaluation of these models, statistical analysis, and others relevant literature.

• What you have the most trepidation about: My background is not in immunology or virology. While I want to contribute, I also want to ensure that the most qualified experts are given the most space/center stage, and that I don’t encroach upon this.

[marouenbg]

Hi everyone!

• Your name: Marouen Ben Guebila
• Your job other than this review: I am a postdoc at the biostatistics department at Harvard School of Public Health.
• What you hope to get out of participating: Contribute a tiny bit to inform the public and the scientific community about the latest development of COVID-19
• How you feel best prepared to contribute: I am also a Pharmacist and I felt I needed to step up when I saw people speculating about the efficacy of drugs without any evidence. I can help substantially in the drug repurposing section of the review.
• What you have the most trepidation about: Virology is not the primary focus of my research, therefore I will stick to what I know best.

[dziakj1]

Hello!

Your name: John J. Dziak Your job other than this review: Research associate professor, The Methodology Center, Penn State What you hope to get out of participating: Contribute my talent in a small way at this critical time How you feel best prepared to contribute: Searching for information on the Internet What you have the most trepidation about: My lack of medical knowledge; difficulty analyzing data due to strict data protection policies at my institution Here are some links I found that might be helpful: https://bestpractice.bmj.com/topics/en-gb/3000165/ https://www.cochranelibrary.com/collections/doi/SC000040/full https://www.ipcrg.org/news/covid-19-open-source-sources-of-information https://www.dropbox.com/s/1jvsqd2quphukqt/RuDASA%20COVID-19%20in%20a%20Rural%20Setting-1.pdf?dl=0 https://www.ncbi.nlm.nih.gov/research/coronavirus/ https://openwho.org/courses/COVID-19-IPC-EN https://www.who.int/emergencies/diseases/novel-coronavirus-2019/technical-guidance

Sachin Shah, a scientist from UCSF, has put together this large collection of academic articles on COVID-19: https://ucsf.app.box.com/s/2laxq0v00zg2ope9jppsqtnv1mtxd52z/folder/107867635118

[kexinhuang12345]

Your name: Kexin Huang Your job other than this review: MS student in Health Data Science at Harvard, working with Prof. Marinka Zitnik at DMBI and Prof. Jimeng Sun at UIUC. What you hope to get out of participating: I want to learn more about how ML could help tackle COVID-19 and potentially engage in one project. How you feel best prepared to contribute: my background is in CS&math, so I could contribute to the more method side review on ML for drug repurposing, including network-based, literature-based, chemical-based and etc.
What you have the most trepidation about: I don't have a formal domain training, would love to learn more from fellow domain experts

[hufengling]

Your name: Fengling Hu Your job other than this review: I am an MD-PhD student in Biostatistics at Perelman School of Medicine. What you hope to get out of participating: I want to contribute to important work and read literature in broad fields. How you feel best prepared to contribute: My background is in statistics, RCTs, machine learning and the like. I'd love to contribute/write on these topics. What you have the most trepidation about: I have strong background in these fields above, but acknowledge I am an early-phase student. I'd love to be a part of conversations with domain experts where I can learn from them while still offering insights about statistics/data. I would be worried if my contributions were not reviewed for accuracy.

[rishirajgoel]

Hi all,

Your name: Rishi Goel

Your job other than this review: MD student at Penn

What you hope to get out of participating: learn more about COVID-19 and help consolidate information to inform the public and scientific community

How you feel best prepared to contribute: my academic/research background is in immunology (feel quite comfortable reading/writing in this area). I worked on vaccine development for 4 years as an undergraduate at Michigan. I also completed a master's degree in immunology where I investigated immune responses to chronic hepatitis C virus infection. Most recently, I worked at the NIH where I studied the pathogenesis of autoimmune diseases like lupus and RA. I am especially interested in discussing experimental therapies for COVID that have a crossover with rheum e.g. HCQ and tocilizumab

What you have the most trepidation about: never done a crowd-sourced review but excited to see how different ideas may develop

[allucas]

Your name: Alfredo Lucas

Your job other than this review: I am an MD-PhD student in Bioengineering at the University of Pennsylvania

What you hope to get out of participating: I hope to become more informed about current developments in COVID related research, and be able to succinctly, but clearly, explain new developments to those not heavily involved in scientific research

How you feel best prepared to contribute: I have both a Bachelor's and Master's degree in Bioengineering, with a focus in the application of machine learning for the development of predictive models in cardiovascular and neurological diseases. I have also experience in medical imaging (both optics and radiology), which becomes relevant in the development of quantitative assays for in vitro diagnostic approaches. I also have past experience in medical device and microfluidic design, and rapid prototyping, which can become relevant in assessing potential engineering solutions to the rapid changing environment of the COVID pandemic

What you have the most trepidation about: I have never worked in this type of collaborative environment before, but I am very eager to try it out

[dianerafi]

Your name: Diane Rafizadeh

Your job other than this review: I am an MD-PhD student in Chemistry at the University of Pennsylvania.

What you hope to get out of participating: I'm hoping to become informed about where the scientific community stands with respect to COVID-19 and the diffuse research that's out there. I'm excited to help curate a centralized resource of information on the subject as it evolves, which I feel is necessary for all scientists and physicians as well as the lay public. It will be especially helpful to have a measure of how strong the evidence is for a given claim that floats around on social media and in the news.

How you feel best prepared to contribute: I am interested in therapeutics and drug design as part of my future career, and am excited to use that interest here. I have strong scientific and non-scientific writing skills.

What you have the most trepidation about: I don't have very much prior experience with viruses and infectious diseases; I have more experience with cancer biology.

[Jeff-Field]

Your name: Jeffrey Field

Your job other than this review: Professor Pharmacology, UPenn

What you hope to get out of participating: Assist in evaluating literature, learn about Covid

How you feel best prepared to contribute: I have taught pharmacology for many years and can help evaluate evidence underlying treatment strategies, especially targeted treatments. In areas I cannot evaluate myself, I can also use my network to direct questions to those who are better equipped.

What you have the most trepidation about: My background is primarily cancer research, though I my thesis on adenovirus, it was a long time a go in a research galaxy far far away...

[nolankav]

Your name: Nolan M. Kavanagh

Your job other than this review: MD student at the University of Pennsylvania and adjunct clinical lecturer at the University of Michigan.

What you hope to get out of participating: Understanding how scientific and clinical information can be efficiently synthesized and distributed for COVID. I'm also intrigued about how the structure of a collaboration like this could coordinate experts on other issues.

How you feel best prepared to contribute: I am most useful for statistical analysis, writing, and working through policy/political implications. My background is in public health and health policy; I did my M.P.H. at Michigan. I continue to research policy/politics, e.g. on the relationship between health and voting. I also teach a biostatistics course at the University of Michigan.

What you have the most trepidation about: Whether or not my skill set will add value or just get in the way... But there might be a health policy angle in here somewhere.

[ressy]

• Your name: Jesse Connell
• Your job other than this review: Bioinformatician for Shaw/Hahn groups at the University of Pennsylvania
• What you hope to get out of participating: I was already working on getting up to speed as quickly as possible on immunology and antibody development concepts for a set of SIV/HIV projects here, and I expect there'll be a lot of overlap in the basic concepts-- I hope to add to an important and meaningful project, and also to learn more immunology and virology along the way.
• How you feel best prepared to contribute: I'm no expert in these topics but I'm comfortable with a lot of the tools potentially in use here and have a knack for troubleshooting in HPC environments, so I could try to dig into raw data associated with papers where publicly-available, in addition to reading and summarizing where I can. I could also pitch in with "backend" organizational tasks if needed (though it sounds like there's plenty of git experience to go around already)
• What you have the most trepidation about: As others have mentioned I don't want to misunderstand any primary data or misinterpret these papers or preprints. This would also be the first big crowdsourced project I've jumped into, and I'll need to juggle time commitments carefully.

[nafisajadavji]

Your name: Nafisa Jadavji Your job other than this review: Assistant Professor at Midwestern University, where I teach, and run a research lab. Most recently, I have also taken on the job of being a home school teacher to a 6th grader. What you hope to get out of participating: Learn more about the virus and potential therapies from primary sources and not the news. How you feel best prepared to contribute: I love to read scientific literature. What you have the most trepidation about: My days are packed with added responsibilities, but I am interested in contributing.

[raghuyennamalli]

Your name: Ragothaman M Yennamalli

Your job other than this review: Assistant Professor at SASTRA University, I teach computational biology to UG and PG students.

What you hope to get out of participating: We are currently working on antivirals for SARS-CoV-2 and this would orient me in the right direction as there is an avalanche of information.

How you feel best prepared to contribute: I have knowledge of Virology as I worked with another RNA enveloped virus, Dengue virus. I am also fairly good at reading literature and hope to do my bit towards helping the society.

What you have the most trepidation about: We are under nationwide lockdown until April 14th and there is only so much news I can watch. I have time in hand, but not utilized properly. I need to take my mind off news and concentrate on something that is productive. Like this review paper.

[anskelly]

Your name: Ashwin Skelly

Your job other than this review: MD-PhD student in the Department of Immunology at the University of Pennsylvania

What you hope to get out of participating: I hope to gain a better understanding of the evolution and biology of SARS-CoV-2. I'm especially looking forward to learning more about the host immune response to the virus and how we can leverage this to develop effective therapeutics and vaccines.

How you feel best prepared to contribute: I have a strong background in immunology, particularly relating to host-microbe interactions -- I studied the microbiome for 4 years at Harvard and 2 years at Keio University in Japan. I also have experience writing literature reviews, and would be excited to contribute to the synthesis, drafting, and editing of this manuscript.

What you have the most trepidation about: I don't have much experience in virology, so I'm a little anxious about the learning curve when it comes to reading and succinctly summarizing articles in this area. I've also never written a collaborative-style review like this, but I'm excited to learn a lot and contribute in any way I can! :)

[johnbarton]

Your name: John Barton

Your job other than this review: I'm an Assistant Professor of Physics at the University of Californa, Riverside. My group is computational, and we focus on the development of statistical inference methods and mathematical modeling. Our biological focus is on virus evolution and immunity.

What you hope to get out of participating: I'd like to help consolidate knowledge about SARS-CoV-2 and COVID-19 as it becomes available.

How you feel best prepared to contribute: I experience with Bayesian inference methods and mathematical modeling, as well as some background knowledge in virology and immunology. I might be a good fit for evaluating and summarizing papers that have a computational/inference focus.

What you have the most trepidation about: My knowledge of immunology and virology is mostly in the context of HIV. I'm also juggling childcare with other research and teaching responsibilities, so quick turnaround times may be a challenge.

[bphilipson]

Your name: Ben Philipson Your job other than this review: MD-PhD Student at University of Pennsylvania What you hope to get out of participating: Help disseminate clear and actionable information on COVID-19 How you feel best prepared to contribute: Having recently completed a PhD in Cell and Molecular Biology focusing on CAR T cell biology, I am familiar with writing reviews and interpreting data. I hope that I can combine that experience with my clinical education to contribute actionable recommendations to providers and policy makers. What you have the most trepidation about: Being useless. I am not exactly sure how to contribute effectively using this interface with so many people.

[catherinedawn]

Hi everyone!

Your name: Catherine LeBlanc

Your job other than this review: biochemistry undergrad at Northeastern University; research assistant for the Lewis Lab/Antimicrobial Discovery Center

What you hope to get out of participating: to learn more about COVID-19 and virology overall

How you feel best prepared to contribute: I have had a lot of experience reading scientific literature

What you have the most trepidation about: being one of the youngest (i.e. least experienced) of the group here, I might not be adding much value to the project

[rdilley]

Your name: Robert Dilley Your job other than this review: MD-PhD student at Penn What you hope to get out of participating: Learn more about COVID-19 and provide useful knowledge to the medical and scientific communities. How you feel best prepared to contribute: I recently finished my PhD in cell/molecular biology. I have a particular interest in the treatment of COVID-19 in patients with active comorbid conditions. What you have the most trepidation about: I've never participated in a review like this.

[boxiangliu]

Your name: Boxiang Liu Your job other than this review: I am a senior research scientist at Baidu Research Institute. Prior to that, I completed my PhD training in bioinformatics from Stanford University. What you hope to get out of participating: I would like to learn more about COVID-19 from peers and provide useful knowledge to the community. How you feel best prepared to contribute: As part of my job, I am optimizing RNA vaccines for COVID-19, as well as studying the evolution of COVID-19 using genetic data. I would be keen to review papers on vaccines and genetics of COVID-19. What you have the most trepidation about: I am writing two other papers at the time, so I might be crunched for time.

[ajlee21]

Your name Alexandra Lee Your job other than this review I am a third year Genomics and Computational Biology PhD student in Casey Greene's lab What you hope to get out of participating To learn more about CoV family and to improve my critical reading skills How you feel best prepared to contribute I have studied viruses (though not specifically CoV) at my previous job. I also had previous coursework studying epidemiological models. I think I could help to peer review basic biology about the virus and contribute sections about the background of the virus. What you have the most trepidation about I have never participated in a review like this before, specifically of this scale so trying to contribute feels a bit daunting.