marouenbg
commented
3 years ago Which areas of expertise are particularly relevant to the paper?
- [ ] virology
- [ ] epidemiology
- [ ] biostatistics
- [x] immunology
- [ ] pharmacology
- [ ] other:
Summary
Suggested questions to answer about each paper:
-
What did they analyze? Estimated transmissibility of the B1.1.7 SARS-CoV-2 Variant in England.
-
What methods did they use? Mathematical modeling.
-
Does this paper study COVID-19, SARS-CoV-2, or a related disease and/or virus? This paper is about the evolution of SARS-CoV-2 into a variant called B1.1.7
-
What is the main finding (or a few main takeaways)? This preprint suggests that the variant B1.1.7 is more infectious and outcompetes other variants by acquiring a competitive advantage.
-
What does this paper tell us about the background and/or diagnostics/therapeutics for COVID-19 / SARS-CoV-2? This paper tells us about the spread of the new variant B1.1.7 in England. Related to #776 , a mutation that increases the affinity of SARS-CoV-2 towards human ACE2 is present in this variant possibly because of selection pressure.
-
Do you have any concerns about methodology or the interpretation of these results beyond this analysis? None
Title: Estimated transmissibility and severity of novel SARS-CoV-2 Variant of Concern 202012/01 in England
General Information
Please paste a link to the paper or a citation here:
Link: https://www.medrxiv.org/content/10.1101/2020.12.24.20248822v1
What is the paper's Manubot-style citation?
Citation: @doi:10.1101/2020.12.24.20248822
Is this paper primarily relevant to Background or Pathogenesis?
Please list some keywords (3-10) that help identify the relevance of this paper to COVID-19
Please note the publication / review status