Closed gwaybio closed 6 years ago
Steps:
This will require:
As discovered in #95 - I will need to perform pathway coverage tests for high weight genes defined by standard
and dynamic
procedures.
This issue has been automatically marked as stale because it has not had recent activity. It will be closed if no further activity occurs. Thank you for your contributions.
A good indicator of "how much biology did the model learn" is based on a pathway coverage test. I need to see how this was done in the
eADAGE paper
and then perform the pathway coverage on Pan-Cancer data for dimensionality reduction algorithms: PCA, ICA, NMF, ADAGE, and Tybalt.Is there a better pathway database for cancer? Perhaps something like KEGG cancer?