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griffithlab / pVACtools

http://www.pvactools.org
BSD 3-Clause Clear License
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NetChop SSLError #1111

Closed Tseng722 closed 1 month ago

Tseng722 commented 1 month ago

Installation Type

Standalone

pVACtools Version / Docker Image

4.0.2

Python Version

No response

Operating System

No response

Describe the bug

pvacbind run myfile.fasta tttt HLA-A*01:01 NetMHCpan NetMHC myfile -e1 9 -k
-t 48 -b 100000 --aggregate-inclusion-binding-threshold 100000
--net-chop-method cterm
--netmhc-stab
--iedb-install-directory my_path

When I use the command above, I came up with error below:

Submitting remaining epitopes to NetChop requests.exceptions.SSLError: HTTPSConnectionPool(host='services.healthtech.dtu.dk', port=443): Max retries exceeded with url: /cgi-bin/webface2.cgi (Caused by SSLError(SSLCertVerificationError(1, '[SSL: CERTIFICATE_VERIFY_FAILED] certificate verify failed: certificate has expired (_ssl.c:1129)')))

How can I solve this problem, thanks

How to reproduce this bug

pvacbind run myfile.fasta tttt HLA-A*01:01 NetMHCpan NetMHC  myfile
-e1 9 
-k  
-t 48 
-b 100000 
--aggregate-inclusion-binding-threshold 100000  
--net-chop-method cterm  
--netmhc-stab   
--iedb-install-directory my_path

Input files

No response

Log output

Submitting remaining epitopes to NetChop requests.exceptions.SSLError: HTTPSConnectionPool(host='services.healthtech.dtu.dk', port=443): Max retries exceeded with url: /cgi-bin/webface2.cgi (Caused by SSLError(SSLCertVerificationError(1, '[SSL: CERTIFICATE_VERIFY_FAILED] certificate verify failed: certificate has expired (_ssl.c:1129)')))

Output files

No response

susannasiebert commented 1 month ago

It looks like their website is was temporarily down due to their SSL certificate expiring. As far as I can tell, that has been resolved and you should be able to restart your run.