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griffithlab / pVACtools

http://www.pvactools.org
BSD 3-Clause Clear License
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Add reference proteome Blast step to pVACvector #519

Open susannasiebert opened 4 years ago

susannasiebert commented 4 years ago

When running with an input fasta we would blast each fasta sequence.

In cases where the input is a pVACseq list of epitopes (+ VCF), we need to further discuss which sequence to blast. If blasting larger sequence for each epitopes we would almost certainly get false-positive hits to the reference proteome around the mutation position.

susannasiebert commented 8 months ago

Note from today's meeting: blast the junctional epitopes.