I think this has come up before, but it'd be immensely helpful to add a bit of information in the README
What is the minimum system requirements (and aws node types) for whole genome alignment?
Is there a function of RAM / video RAM that can be used to guide node selection based on input size?
What are the hardcoded size limits? Is it exactly 3G? From a Cactus standpoint, it doesn't really matter, save for the fact that it needs to be known exactly a priori.
I think this has come up before, but it'd be immensely helpful to add a bit of information in the README