Closed gszep closed 6 years ago
Figure 1 : Steady state levels of L,T in cyan,yellow respectively as a function of c,c' with parameters taken from CRN file demonstrating neither bistability nor exclusivity are present
Figure 2 : Steady state levels of L,T in cyan,yellow respectively as a function of c,c' demonstrating both bistability and exclusivity with other parameter sets
The simulations carried out with crn tool with this code demonstrate that no matter the initialisation with
c6
or c12
the system will tend towards expressing only cfp
, consistent with analytical
results in Figure 1.
Here we have plotted ([cfp]-[yfp])/([cfp]+[yfp])
which is a measure between -1 and 1
reveals to us the relative dominance of concentration regardless of magnitudes. The worrying
thing is that Figure 4 suggests that the observed boundary sharpening may actually be a
transient in a longer timescale equilibration process.
Figure 3 : Spacetime plot of L,T in one dimensional simulation, with only c6
initialised as a central core
Figure 4 : Spacetime plot of L,T in one dimensional simulation, initialised with mutually
exclusive domains of c6
and c12
showing transient sharp boundary dissolving into a
sea of cfp
Figure 5 : Spacetime plot of L,T in one dimensional simulation, with only c12
initialised as a central core
currently activators R,S are displayed as cyan and yellow respectively which results in a display of full cyan and yellow if there are no signalling molecules c,c'. We would like to display L,T instead, which have a steady state of (0,0) when c,c' are not present