gwcbi / haphpipe

NGS viral assembly and population genetics
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Issues with predict_haplo #21

Open marieleoz opened 1 year ago

marieleoz commented 1 year ago

Hi guys,

Thanks a lot for HAPHPIPE, I've used it successfully and pretty easily for HRSV and HIV assembly, it did great!

Now we want to get to the next level with HIV haplotype reconstruction, but I am facing issues with predict_haplo. First I only used it with corrected fastq reads and final assembly from a denovo assembly, as exemplified in your tutorial; it looks like bwa-mem did ok but then i get:


Reconstruction region PH01: RBF254|RBF254|RBF254:1-9024

[--- predict_haplo:PH01_RBF254 command 1 ---] cd \ /tmp/tmpHP_predict_haplonazqau_x

[--- predict_haplo:PH01_RBF254 command 2 ---] PredictHaplo-Paired \ PH01_RBF254.config \ &> PH01_RBF254.config.log /bin/sh : ligne 1 : 3424 Erreur de segmentation PredictHaplo-Paired PH01_RBF254.config &>PH01_RBF254.config.log

[--- FAILED: predict_haplo:PH01_RBF254 ---] Command: cd /tmp/tmpHP_predict_haplonazqau_x && PredictHaplo-Paired PH01_RBF254.config &> PH01_RBF254.config.log returncode: 139 PredictHaplo segfaulted


I wonder if this is related to the lack of an interval_txt option, but:

Please can you help me out of this? I attach a log file for the run with no --interval_txt option: slurm-48131535.out.txt

as well as the ref fasta file: RBF254_denovo_consensus.fas.txt

Please let me know if you need more to figure this out. Cheers, Marie