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gymrek-lab / EnsembleTR

Tools for merging Tandem Repeat VCF files
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Imputation #14

Closed WeiYang-BAI closed 1 year ago

WeiYang-BAI commented 1 year ago

Hi,

Thanks for this wonderful reference panel for TR imputation! Not an issue, just wondering could I use other tools instead of beagle for the imputation? Would beagle perform better with the panel?

Best,

heliziii commented 1 year ago

Hi! I'm sorry for the late reply. You surely can use other tools for imputation. However, based on our experience, Beagle works more accurately in the imputation of multi-allelic sites like TRs.

Best, Helia

WeiYang-BAI commented 1 year ago

See it, thanks Helia!

Best, Weiyang