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hakyim / TO-DELETE-PrediXcan

Code for the in-dev PrediXcan Project
MIT License
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A Query Regarding Sample size #31

Open waqasuddinkhan opened 5 years ago

waqasuddinkhan commented 5 years ago

Hi,

I do not have an exact issue. I have a query. What would be minimum sample size (How many controls, and how many cases???)one needs to predict the gene expression by PrediXcan?

Thanks in advance,

Waqas.

hakyim commented 5 years ago

You can predict in any sample. If you want to find genes associated with a trait, as a general rule you would need enough samples to get some GWAS significant loci. If you are only looking into a smaller genomic region you may need less samples.

I hope this helps

On Thu, Nov 15, 2018 at 10:50 PM waqasuddinkhan notifications@github.com wrote:

Hi,

I do not have an exact issue. I have a query. What would be mainimum sample size (How many controls, and how many cases???)one needs to predict the gene expression by PrediXcan?

Thanks in advance,

Waqas.

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waqasuddinkhan commented 5 years ago

Thanks hakyim...,,,!!!!

Actually we have 21 cases and 21 controls and 28 genetic variants (let's say in 10 genes) only, and for that, we want to run PrediXcan, hope it is quite enough?

hakyim commented 5 years ago

Well, those numbers are a lot smaller than what we normally use.

Haky

On Wed, Nov 21, 2018 at 7:16 AM waqasuddinkhan notifications@github.com wrote:

Thanks hakyim...,,,!!!!

Actually we have 21 cases and 21 controls and 28 genetic variants (let's say in 10 genes) only, and for that, we want to run PrediXcan, hope it is quite enough?

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