halasadi / ancient-structure

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Meeting Summary #13

Closed halasadi closed 9 years ago

halasadi commented 9 years ago

1). What is the problem we are tackling? What have previous studies done and what are their flaws

See : https://github.com/halasadi/ancient-structure/blob/master/docs/Matthew%20report/introduction.pdf

2). Exploratory data analysis on the data : PCA and general Admixture

See : https://github.com/halasadi/ancient-structure/blob/master/docs/Matthew%20report/plot_exploratory.pdf

3a). Talk about the basic model without sampling correction.

See: https://github.com/halasadi/ancient-structure/blob/master/docs/Matthew%20report/model_1.pdf

3b). We simulated under the WF model. Show the drift factor and how it's not a problem. Show how finite sample size can introduce a lot of error.

See : http://htmlpreview.github.com/?https://github.com/halasadi/ancient-structure/blob/master/docs/Matthew%20report/example_sim_drift_old.html

3c). Show the real data analysis

See: http://htmlpreview.github.com/?https://github.com/halasadi/ancient-structure/blob/master/docs/Matthew%20report/Haak_data_analysis_model_1.html

4). We've developed a modification and show the doc that we've prepared.

See : https://github.com/halasadi/ancient-structure/blob/master/docs/Matthew%20report/model_2.pdf

5a). Under the new model, show results under simulations with and without drift and talk about sampling correction

See: https://github.com/halasadi/ancient-structure/blob/master/docs/Matthew%20report/example_sim_drift_new.pdf

5b). Apply the new model to the Haak Human Origins data

See: http://htmlpreview.github.com/?https://github.com/halasadi/ancient-structure/blob/master/docs/Matthew%20report/Haak_data_analysis_model_2.html

6). Discussions

See: http://htmlpreview.github.com/?https://github.com/halasadi/ancient-structure/blob/master/docs/Matthew%20report/discussion.html