halbritter-lab / kidney-genetics

Kidney-Genetics - database of kidney-related genes
MIT License
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Implement interaction data from StringDB for manual curation #22

Closed berntpopp closed 10 months ago

berntpopp commented 10 months ago

Use StringDB to download tables (https://string-db.org/cgi/download?sessionId=bVJC28yKCRz5&species_text=Homo +sapiens). Only the physical interactions are required (https://stringdb-downloads.org/download/protein.physical.links.v12.0/9606.protein.physical.links.v12.0.txt.gz). Sum the interactions with the high evidence list for each gene, then percentile normalize and display a string with interacting genes and scores in an additional column. Add a column with defined cutoffs (0 points for less than one standard deviation, 0.5 points for more than one standard deviation, and 1 point for more than two standard deviations).

TODO: