Thank you for developing such a great tool! I would like to confirm some of my understanding of setting up the expr_mat. I sliced the single-cell expression matrix to only the marker genes. This way, the gene dimension of expr_mat matches marker_onehot.
Another way to make this dimension match is to keep the expression matrix as it is and make marker_onehot larger. In other words, I can fill in the non-marker genes in marker_onehot as all zeros for all columns.
I think this makes no difference compared with only keeping the marker genes in expr_mat, but could you please confirm this?
Thank you for developing such a great tool! I would like to confirm some of my understanding of setting up the expr_mat. I sliced the single-cell expression matrix to only the marker genes. This way, the gene dimension of expr_mat matches marker_onehot.
Another way to make this dimension match is to keep the expression matrix as it is and make marker_onehot larger. In other words, I can fill in the non-marker genes in marker_onehot as all zeros for all columns.
I think this makes no difference compared with only keeping the marker genes in expr_mat, but could you please confirm this?