Closed kzuberihmf closed 4 months ago
Small change, clonal likelihood adjustment applied in GermlineConversion.toSomaticVariants(). Since PurpleVariant represents subclonaLikelihood, the conversion works like:
germline VCN > 0.5 -> somatic subclonalLikelihood = 0.0 germline VCN <= 0.5 -> somatic subcloncalLikelihood = 1.0
Orange VarientEntry represents clonalLikelhood directly and converts as (1-subclonal) in VariantEntryFactory, which I'm leaving unchanged.
This branch includes the cuppav2 change, so regression testing will wait a bit.
Small change, clonal likelihood adjustment applied in GermlineConversion.toSomaticVariants(). Since PurpleVariant represents subclonaLikelihood, the conversion works like:
germline VCN > 0.5 -> somatic subclonalLikelihood = 0.0 germline VCN <= 0.5 -> somatic subcloncalLikelihood = 1.0
Orange VarientEntry represents clonalLikelhood directly and converts as (1-subclonal) in VariantEntryFactory, which I'm leaving unchanged.
This branch includes the cuppav2 change, so regression testing will wait a bit.