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harvardinformatics / degenotate

MIT License
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Negative strand variant bug #28

Closed gwct closed 1 year ago

gwct commented 1 year ago

Fixed a bug in which substitutions were miscounted on transcripts on the negative strand because variants in the vcf file are reported on the positive strand. This was fixed by simply complementing the alternate alleles in the vcf that occur on transcripts on the negative strand,