variants from primary tumors and metastasis tumors without normal controls

hdng / clonevol

Inferring and visualizing clonal evolution in multi-sample cancer sequencing

GNU General Public License v3.0

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variants from primary tumors and metastasis tumors without normal controls #45

Open qindan2008 opened 3 years ago

qindan2008 commented 3 years ago

Hello, I have 10 pairs of samples. They're paired primary and metastasis tumors, but none of them have normal controls. Can variants called by mutect2 or other snp callers be used by SciClone and ClonEvol ? The variants are just mixtures of germline and somatic mutations. I just want to know about tumor clone and evolution.

Thank you very much.