input blood transcriptome

hessJ / BrainGENIE

Brain Gene Expression and Network Imputation Engine

MIT License

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input blood transcriptome #4

Open lyj95618 opened 9 months ago

lyj95618 commented 9 months ago

Hi,

I am trying to use GrainGENIE to impute gene expression from my blood RNAseq. I am wondering if there are any requirements for the input blood transcriptome data frame, for example, would the raw counts from featurecount be suitable as the input? or I need to do some normalization before inputting?

Thanks! Laur

hessJ commented 1 month ago

Normalization of raw RNAseq data is recommended, otherwise the output from BrainGENIE will not be reliable.