Closed alexvpickering closed 5 years ago
No impressive difference between techs (AUC Microarray: 0.759, RNA-Seq: 0.727):
One observation that aligns with previous observations (single signatures generated for each compound perform worse than individual signatures for each compound_cell_dose) is that sorting by minimum correlation has a benefit over sorting by average correlation (AUC min: 0.759, avg: 0.672):
Same but for RNA-Seq (AUC min: 0.727, avg: 0.664):
It would be useful to know for future datasets that we might generate. Here are some studies that have profiled CMAP02 drugs using both RNA-Seq and microarray platforms: