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hms-dbmi / scde

R package for analyzing single-cell RNA-seq data
http://pklab.med.harvard.edu/scde
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Computing the statistical significance of overdispersion #75

Open livnatje opened 5 years ago

livnatje commented 5 years ago

Is it possible to compute the p-value of overdispersion for given gene sets in a more strict manner as done for the denovo identified pathways?

The gene sets I'm working with were generated based on gene-gene correlations, so I want to be careful and not estimate the statistical significance of their overdispersion.

Thanks!!! Livnat