iGEM-Engineering / iGEM-distribution

Repository for collective design of an iGEM DNA distribution
https://igem-distribution.readthedocs.io
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Script for check DNA sequence synthesizability #289

Open isaacguerreir opened 2 years ago

isaacguerreir commented 2 years ago

Adapt tool from Salis Lab to analyze Synthesis Sucess of DNA Sequence and create a script to check synthesizability of distribution parts produced.

isaacguerreir commented 2 years ago

I will return to the first idea of using IDT API, so we don't need to worry about new rules and challenges of future improvements of synthesis technology.

noahsprent commented 1 year ago

Quoting Jake's comment from duplicate issue #34 so we can close that one:

Twist has an API for scoring, which we can potentially use to automate score checking https://twistapi.docs.apiary.io/#

Note that they limit the rate at which scoring can be run, so this would need to be run more slowly than some of the other checks, and would want to use caching to avoid re-scoring the same sequences.