HMM-based CNV caller - Githubissues

icbi-lab / infercnvpy

Infer copy number variation (CNV) from scRNA-seq data. Plays nicely with Scanpy.

https://infercnvpy.readthedocs.io/en/latest/

BSD 3-Clause "New" or "Revised" License

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Open grst opened 3 years ago

grst commented 3 years ago

inferCNV uses a hidden markov model to turn the smoothed gene expression into genomic regions that are subject to CNV.

Would be nice to implement a similar feature here.

Liripo commented 1 month ago

Hello: This package performs very well, is there any progress on HMM?

grst commented 1 month ago

I'm happy to accept a pull request that enables some sort of segmentation, but I don't have the time to implement it myself.