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icbi-lab / quanTIseq

a computational pipeline for the quantification of the Tumor Immune contexture from human RNA-seq data
https://icbi.i-med.ac.at/software/quantiseq/doc/index.html
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NK cells phenotype #15

Open iranmdl opened 2 years ago

iranmdl commented 2 years ago

Hi! Are the NK cells in the output of quantiseq, activated NK cells or resting/inactive NK cells? Is the NK cell data used for "training" quantiseq made of active NK cells or resting?

Thank you in advance, Irantzu

FFinotello commented 2 years ago

Hello @iranmdl

You can find detailed information for all cell-type-specific expression profiles used for quanTIseq signature in the Additional File 1. NK cell profiles, specifically, are from Linsey et al. and Hoek et al. studies.

I hope this helps.

Francesca