icgc-argo / argo-dictionary

Development of the ARGO Data Dictionary
https://docs.icgc-argo.org/dictionary
GNU Affero General Public License v3.0
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Feature Request: Create new treatment table for Immunotherapy #110

Closed hknahal closed 3 years ago

hknahal commented 4 years ago

As discussed with working group:

In our dictionary, we use the term “Monoclonal antibodies (for liquid tumours)”. However, monoclonal antibodies are not always associated with liquid tumours. For example, in breast cancer HER+, patients get treated with monoclonal antibodies (sometimes called immunotherapy). Proposed the following changes:

Instead of the two current categories “Immunotherapy” and “Monoclonal antibodies” use: Immunotherapy, monoclonal antibodies other than immune checkpoint inhibitors Immunotherapy, immune checkpoint inhibitors Immunotherapy, cell-based Immunotherapy, other immunomodulatory substances

Detailed Description

  1. Will remove the term Monoclonal antibodies (for liquid tumours) from the treatment_type codelist and leave just Immunotherapy

  2. Will create a separate treatment table called Immunotherapy with the following fields (to begin with):

    • program_id
    • submitter_donor_id
    • submitter_treatment_id
    • immunotherapy_type which will include a codelist with the following terms:
  3. Immunotherapy, monoclonal antibodies other than immune checkpoint inhibitors

  4. Immunotherapy, immune checkpoint inhibitors

  5. Immunotherapy, cell-based

  6. Immunotherapy, other immunomodulatory substances

Will most likely add a few more fields to this table after gathering more information from working group.

hknahal commented 3 years ago

This is related to https://github.com/icgc-argo/argo-dictionary/issues/240 so will close this ticket since it's duplicated.