In the current data model, specimen_acquisition_interval indicates the interval between primary diagnosis and specimen acquisition in days. It is an integer larger than 0.
However, for program MONSTAR,
They use date of enrolment as date of diagnosis
Their tissue NGS is performed with archival tissue for the majority of cases, so sample collection is often performed prior to enrolment
Considering the specimen table can be expanded to collect any specimens associated with a donor not only related to one given diagnosis. We can allow the specimen_acquisition_interval to accept negative numbers.
In the current data model,
specimen_acquisition_interval
indicates the interval between primary diagnosis and specimen acquisition in days. It is an integer larger than 0.However, for program MONSTAR,
Considering the specimen table can be expanded to collect any specimens associated with a donor not only related to one given diagnosis. We can allow the
specimen_acquisition_interval
to accept negative numbers.Implementation