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igvteam / igv-webapp

IGV Web App
https://igv.org/app
MIT License
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Methylation data disappears from bigwig tracks #306

Closed dvl-romero closed 3 hours ago

dvl-romero commented 3 hours ago

Hi,

I have a Granges object of 270 ranges that I've converted into a BigWig file then loaded onto IGB (ver 8.3.2). On Chr21, I have 2 differentially methylated regions (DMR), when viewing the entire chromosome. Notice the far right DMR near the 34,129,343 position. image (2)

However, when I zoom into that region -even just a little- , the DMR completely disappears. I've tried zooming directly at the specific genomic region (start and end position), but even then, the region does not show up. image (2) copy

I know I haven't changed the Y-axis scale of that track or visibility options (I'm using filled bar), and I'm sure the genomes of my Bigwig file and reference match (Hg38 Human). The problem persists regardless of the number of tracks I load into the browser, and it also occurs in the IGV web browser.

Is there something I'm missing? Any advice is appreciated!

jrobinso commented 3 hours ago

Hi, sorry but this is the IGV (Integrative Genomics Viewer) github. I can't help with IGB.