Added error and median quality filters

immcantation / presto

pRESTO is part of the Immcantation analysis framework for Adaptive Immune Receptor Repertoire sequencing (AIRR-seq). pRESTO is a bioinformatics toolkit for processing high-throughput lymphocyte receptor sequencing data.

https://presto.readthedocs.io

GNU Affero General Public License v3.0

0 stars 0 forks source link

Added error and median quality filters #26

Closed ssnn-airr closed 6 years ago

ssnn-airr commented 9 years ago

Original report by Jason Vander Heiden (Bitbucket: javh, GitHub: javh).

We should probably change the quality filtering in FilterSeq from mean to median and/or add an error count method as per http://drive5.com/usearch/manual/avgq.html.

ssnn-airr commented 6 years ago

Original comment by Jason Vander Heiden (Bitbucket: javh, GitHub: javh).

Closing. Has never been a need and given my generate distrust of quality score accuracy, I'm skeptical of the benefit.