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immunogenomics / SCENT

Single-Cell ENhancer Target gene mapping using multimodal data with ATAC + RNA
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Is it possible to use SCENT for Bulk RNAseq data? #11

Closed cparsania closed 3 weeks ago

cparsania commented 3 weeks ago

Hi,

I wonder if I can trick SCENT for bulk RNAseq data

Cheers Chirag.

saorisakaue commented 3 weeks ago

Hello,

No, our method is specifically designed for handling single-cell resolution discrete count data of ATAC-seq and RNA-seq. If you are interested in bulk ATAC-seq RNA-seq correlation, methods like EpiMap (Boix et al 2021) can be relevant.

Saori