search

immunogenomics / harmony

Fast, sensitive and accurate integration of single-cell data with Harmony
https://portals.broadinstitute.org/harmony/
Other
513 stars 98 forks source link

How to combine/merge three ArchRProject objects #229

Closed qdong2023 closed 9 months ago

qdong2023 commented 9 months ago

Hello,

I have multiple ArchRProject objects to be combined/merged. These ArchR objects were generated from different batches of arrow files/experiments, however, I don't need to do "integration" such as harmony because I have done the batch correction for their multiomic RNA datasets. So I am wondering how to simply combine/merge multiple ArchR objects or if I should import all arrow files and re-create one ArchRproject object? Any suggestion would be greatly helpful!!

Thanks!

pati-ni commented 9 months ago

This is not related to harmony, so I am closing as off-topic.

From what I am reading, your objects look that they correspond to different vector spaces so they should be merged with strategies like Seurat's CCA.

qdong2023 commented 8 months ago

@pati-ni I was asking about the functions in ArchR rather than the harmony. Thanks for your reply though.