search

immunomind / immunarch

🧬 Immunarch: an R Package for Fast and Painless Exploration of Single-cell and Bulk T-cell/Antibody Immune Repertoires
https://immunarch.com
Apache License 2.0
297 stars 65 forks source link

".gene" request for OryctolagusCuniculus TRA, TRB, TRG, TRD #262

Open BinhDiep2021 opened 2 years ago

BinhDiep2021 commented 2 years ago

🚀 Feature

We would really appreciate it if you could add the rabbit OryctolagusCuniculus as a supported species. Specifically, we need the following ".gene": rabbit TRA, TRB, TRG, TRD.

Motivation

The rabbit OryctolagusCuniculus's B cell receptor repertoire is widely used because of the importance of this species in antibody production but its T cell receptor repertoire also need to be characterized for many immunological studies (for example, we need to characterize the T cell receptor repertoire in response to exposure to the rabbit to COVID-19 SARS-CoV-2).

Pitch

Would it be possible if you could create ".gene" for rabbit: TRA, TRB, TRG, TRD? The recently released IMGT library with v8 scripts includes addition of new loci for rabbit TRA, TRB, TRG, TRD. Please see link below: https://github.com/repseqio/library-imgt/releases

Thank you so much for your consideration of this feature request for the immunarch platform.

Binh

MVolobueva commented 2 years ago

Hi, @BinhDiep2021 !

Indeed, it is time for us to update the IMGT database built into the Immunarch:) We will do this in the next release (Immunarch 1.0.0).

Thank you so much for drawing our attention to this. Do not hesitate to contact us with any questions further along.

Best regards, Maria Samokhina