Open peter-yufan-zeng opened 4 years ago
Hi @peter-yufan-zeng ,
Thank you for your suggestion! You help us a lot to make the package more applicable. Can you please send an example of data to the support@immunomind.io with additional chains in order to test?
I think AbStar provides additional chains as well, so adding this to the current issue.
🚀 Feature
Most BCR analysis programs (ex. MIXCR and IMMCANTATION) also output a field with information regarding the constant chain (ex. IGHG1, IGHA1). It would be nice to also load that information into immunarch.
Motivation
BCR constant region is an important characteristic of the repertoire - i.e for proportion of clones in IGHM vs IGHA tells us a lot about what process of affinity maturation/somatic hypermutation the clones is in. So far, when I need to do analysis like this I have always just wrote custom script to reload the data from mixcr.
Pitch
Add an extra field for CREGION
Alternatives
N/A
Additional context