infectious-disease-ontology / infectious-disease-ontology-retired

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new term: seroprotection #31

Open GoogleCodeExporter opened 9 years ago

GoogleCodeExporter commented 9 years ago
Hi,

I am looking at adding seroprotection into InfluenzO, and I was wondering if 
this is something IDO would want to take care of?
definition: a disposition conferred to an organism following vaccination. 

paper with more information: http://www.ncbi.nlm.nih.gov/pubmed/15163500

If we use the vaccination process from VO, we would consider only "successful" 
vaccination, so I think that would work.

I was wondering if it should be a child of current term "acquired immunity to 
infectious agent", but I was uncertain as its definition (An immunity to 
infectious agent that inheres in an organism in virtue of lymphocytes and 
lymphocyte receptors that came into being as a result of a primary immune 
response in that organism.) specifically mentions lymphocytes, which as far as 
I can tell are not evaluated in the hemagglutination-inhibition test.

Thanks,
Melanie

Original issue reported on code.google.com by mcour...@gmail.com on 3 May 2011 at 9:31

GoogleCodeExporter commented 9 years ago
Hi Melanie,

I would suggest that if 'seroprotection' really is specific to vaccination, 
then the term could go in either IDO or VO.  On the other hand, if the term is 
more general, then it should probably go in IDO.  I would interpret the term to 
refer to protection based on blood/serum components, primarily Ig, regardless 
of the way by which these things came to be in the blood/serum.  For example, 
wouldn't immunodeficient individuals who receive IV immunoglobulin have 
seroprotection in the absence of vaccination.  Additionally, some individuals 
will have seroprotection as a consequence of natural infection.

Lindsay

Original comment by lindsay....@utsouthwestern.edu on 4 Sep 2011 at 11:13