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insightsengineering / tern

Table, Listings, and Graphs (TLG) library for common outputs used in clinical trials
https://insightsengineering.github.io/tern/
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Add weighted log-rank tests #30

Closed cicdguy closed 1 year ago

cicdguy commented 3 years ago

Besides the log-rank (cox score) p-value, tern currently supports cox wald and likelihood ratio test p-values. Missing are weighted log-rank tests, e.g. Peto-Peto, Gehan-Breslow, etc.

Currently, these tests serve as sensitivity analyses at best (not included in most SAPs). The log-rank test remains the preferred primary analysis for time-to-event endpoints by regulatory agencies. So the question comes down to how much we prioritize primary vs secondary analysis of clinical endpoints.

NEST/tlg-catalog/pull/611 Provenance: ``` Creator: anajens ```
cicdguy commented 3 years ago

@danielinteractive do you think we should prioritize this?

Provenance: 

Creator: anajens
cicdguy commented 3 years ago

@anajens I would wait for teams asking for this

Provenance: 

Creator: danielinteractive
shajoezhu commented 1 year ago

closing low-priority, prior 2021 December issues