iqbal-lab-org / gramtools

Genome inference from a population reference graph
MIT License
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Release 1.6.0 #154

Closed bricoletc closed 4 years ago

bricoletc commented 4 years ago

In this release we want a stable version of gramtools for use by minos. I propose b95321b.

I ran a pipeline to compute Mendelian errors from Plasmodium crosses and found:

MendErr_rate_all

MendErr_rate_all

x-axis is filtering sites by increasing 5-percent quantiles of GT CONF.

We get the same Mend error rate with no filtering: 6.5 x 10e-04

This is slightly higher than the analysis I ran in May using e66865e, at 5.0 x 10e-04.

This could be due to code changes OR having then analysed 52 samples genome wide rather than 20 samples on chroms 1&2.

bricoletc commented 4 years ago

@iqbal-lab @martinghunt sound OK?

iqbal-lab commented 4 years ago

when you say "We get the same Mend error rate" - same as what?

bricoletc commented 4 years ago

between the two commits shown

iqbal-lab commented 4 years ago

ah i see, ok by me!

martinghunt commented 4 years ago

Looks good to me 👍