In this release we want a stable version of gramtools for use by minos. I propose b95321b.
I ran a pipeline to compute Mendelian errors from Plasmodium crosses and found:
958fd53 : the commit that current latest minos uses
cf5cc20 : the version I propose using (minus 1 commit; b95321b adds a CLI bugfix). Main change is it uses a coverage graph to store and output per base coverage
x-axis is filtering sites by increasing 5-percent quantiles of GT CONF.
We get the same Mend error rate with no filtering: 6.5 x 10e-04
This is slightly higher than the analysis I ran in May using e66865e, at 5.0 x 10e-04.
This could be due to code changes OR having then analysed 52 samples genome wide rather than 20 samples on chroms 1&2.
In this release we want a stable version of gramtools for use by minos. I propose b95321b.
I ran a pipeline to compute Mendelian errors from Plasmodium crosses and found:
x-axis is filtering sites by increasing 5-percent quantiles of GT CONF.
We get the same Mend error rate with no filtering: 6.5 x 10e-04
This is slightly higher than the analysis I ran in May using e66865e, at 5.0 x 10e-04.
This could be due to code changes OR having then analysed 52 samples genome wide rather than 20 samples on chroms 1&2.