Reminder of an issue we discussed previously. Removing kmers from a probe which are known to occur elsewhere might improve the robustness of genotyping. One reason this matters is when we start messing around with changing the kmer; dropping the kmer will increase the chances of part of the probe existing elsewhere.
Phelimb
commented
5 years ago
Reminder of an issue we discussed previously. Removing kmers from a probe which are known to occur elsewhere might improve the robustness of genotyping. One reason this matters is when we start messing around with changing the kmer; dropping the kmer will increase the chances of part of the probe existing elsewhere.