search

isop-phmx / studyGroup

Online Pharmacometrics Study Groups
http://isop-phmx.github.io/studyGroup
Other
19 stars 5 forks source link

Proposal: Using a PK/PD model for simulation-based assessment of probability of technical success in drug development. #22

Open kylebaron opened 8 years ago

kylebaron commented 8 years ago
vjd commented 8 years ago

hi Kyle! is this going to be a real world example where a published work can be followed, or will you be providing some background material for folks to have a guess on the approach you may take.

Great proposal! đź‘Ť

kylebaron commented 8 years ago

Do you want to do this June 10?

vjd commented 8 years ago

Can you do this the following week. Folks will be just returning from PAGE. It doesn't have to be a Friday ..

On Thu, Jun 2, 2016, 6:55 AM Kyle Baron notifications@github.com wrote:

Do you want to do this June 10?

— You are receiving this because you commented. Reply to this email directly, view it on GitHub https://github.com/isop-phmx/studyGroup/issues/22#issuecomment-223195386, or mute the thread https://github.com/notifications/unsubscribe/ABXAmpbzxOHJBTcP6jBgNWIk_K6obsZEks5qHmJZgaJpZM4IWrZY .

~Vijay

ghost commented 8 years ago

Yeah ... I'll look for a day the next week.  Thanks for catching that.

KTB

On Thu, Jun 2, 2016, at 06:48, Vijay Ivaturi wrote:

Can you do this the following week. Folks will be just returning from PAGE. It doesn't have to be a Friday ..

On Thu, Jun 2, 2016, 6:55 AM Kyle Baron notifications@github.com wrote:

Do you want to do this June 10?

— You are receiving this because you commented. Reply to this email directly, view it on GitHub https://github.com/isop-phmx/studyGroup/issues/22#issuecomment-223195386 , or mute the thread https://github.com/notifications/unsubscribe/ABXAmpbzxOHJBTcP6jBgNWIk_K6obsZEks5qHmJZgaJpZM4IWrZY .

-- ~Vijay

— You are receiving this because you are subscribed to this thread. Reply to this email directly, view it on GitHub[1], or mute the thread[2].

Links:

  1. https://github.com/isop-phmx/studyGroup/issues/22#issuecomment-223268703
  2. https://github.com/notifications/unsubscribe/AOo7HO3zxYiIn-g4R9dSOgUaabbAJX5Dks5qHsMLgaJpZM4IWrZY
kylebaron commented 8 years ago

@vjd June 24?

vjd commented 8 years ago

yup! lets lock it down

vjd commented 8 years ago

@kylebmetrum can you please setup a youtube link so that we can be ready to send out an email blast on Monday

MarioGS commented 8 years ago

None of the links: https://www.youtube.com/watch?v=TqEBhJ1kK3A or https://www.youtube.com/watch?v=ZGv1T9xp9uA&t=0s worked for me. They last less than 5 minutes. Could you please upload the full session? Thanks :)

kylebaron commented 8 years ago

https://www.youtube.com/watch?v=F_oM1V4Lp90

MarioGS commented 8 years ago

Thanks Kyle :+1:

kylebaron commented 8 years ago

The BMI summaries for the two data sets should have been:

> data %>% group_by(set) %>% summarise(mean=mean(BMI))
Source: local data frame [2 x 2]

    set     mean
  <dbl>    <dbl>
1     1 26.95538
2     2 29.54463
kylebaron commented 8 years ago

I mentioned that the PTS literature I was using came from Pfizer pharamcometrics. Ken Kowalski and Matt Hutmacher were already at Ann Arbor Pharmacometrics Group

blalovic commented 8 years ago

Hi Kayle,

Really nice presentation on Friday. Thank you! Will you be able to share the dataset and the .R?

Thanks, Bojan

kylebaron commented 8 years ago

Thanks, @blalovic . I believe this will run if you get all the packages installed: https://github.com/mrgsolve/examples/tree/master/PrTS

People can clone the repo or just download a .zip file here: https://github.com/mrgsolve/examples

Let me know via issue tracker if something isn't there that is required to run and I'll get it updated.