Closed pengzhangzhi closed 1 year ago
For your reference, I try to guide the generated structure to obey a template structure. Here is the trajectory. convert txt to pdb. bb_traj_1.txt
For those who are interested in guiding se3 diffusion, after a few days of debugging and experiments, my conclusions are:
Hi, I'm currently busy with some paper deadlines so can't look in detail. I have a few thoughts.
Hi Jason, I recently worked on guiding the generation of se3 diffusion with a guidance function, similar to classifier guidance. I found the output trajectory Xt satisfies the guidance function very well at t in the middle, when t is close to 0, the Xt is out of control. I think this is because the training of se3 uses many losses to stress on the X0 reconstruction at t close to 0. Not sure if my hypothesisis correct. Do you have any ideas?