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jasperlinthorst / reveal

Graph based multi genome aligner
MIT License
46 stars 3 forks source link

Plant genomes ? #4

Closed colindaven closed 7 years ago

colindaven commented 8 years ago

Hi,

is it worth giving this a go with really nasty repetitive genomes ? I.e. plants with genomes > 2GB ?

I might attempt a test if you'd recommend this. Otherwise, would you more recommend target regions ?

Thanks, Colin

jasperlinthorst commented 8 years ago

Hi Colin, I think it mainly depends on the quality of your de-novo assemblies and the amount of collinear sequence between the genomes, but in general the method should be robust to the repetitiveness. I guess it would be best to target some specific regions first to try to (multi) align those to get the parameters right. If you want I can help out, I would just need some specifics in that case: jasper.linthorst@gmail.com

Cheers, Jasper