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jaydu1 / scVAEIT

Variational autoencoder for single-cell integration and transfer learning.
MIT License
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Available for single modality integration? #6

Closed adamtongji closed 6 months ago

adamtongji commented 6 months ago

Hi, thank you for your tools and paper for multimodal mosaic integration! I hope to integrate datasets of multiome(RNA+ATAC) and scRNA. But your tutorials only mentioned multimodal integrations with at least two modalities. Does scVAEIT support mosaic integration with single modality of scRNA, scATAC or ADT?

jaydu1 commented 6 months ago

Hi, thanks for your interest! Regarding your questions, yes, scVAEIT supports the imputation for multiple datasets with the same modality.

I have added an example to demonstrate the usage in this case example/imputation_1modality.ipynb.

Let me know if you have any questions and if anything needs to be clarified for the parameter setup.