jbloomlab / SARS2-mut-fitness

Observed substitution counts of SARS-CoV-2 compared to those expected under the mutation rates
MIT License
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noncoding mutations now included in actual versus expected counts #24

Closed jbloom closed 1 year ago

jbloom commented 1 year ago

We now include non-coding mutations (calculated via --sample-paths command of matUtils, see here) in the expected versus actual counts. The current amino-acid fitness estimates are unchanged. We still need to add a rule to do the nucleotide fitness estimates, but that should be easy now that we have the counts.