jean997
commented
2 years ago Yes - you can store the LD files locally which I think will help. Try looking here for how to do it https://mrcieu.github.io/ieugwasr/articles/local_ld.html
Closed Rick-Chen-PKU closed 2 years ago
jean997
commented
2 years ago Yes - you can store the LD files locally which I think will help. Try looking here for how to do it https://mrcieu.github.io/ieugwasr/articles/local_ld.html
As shown in the figure below, about 6905720 variants are obtained through the gwas_merge function. Then I pruning with the parameter pval_thresh = 1e-5 and it turns out that there is an error in the api_query i.e. "The query to MR-Base exceeded 300 seconds and timed out. Please simplify the query". Is there any way to solve this problem? Can I randomly reduce my variants? Any solution to this problem is very apprecited. Thanks!