The S2 RNAi project has a large number of libraries. When dealing with this large number of libraries there are bound to be various block effects. When looking at library size differences between libraries we see various block effects (with in and among plates). I want to estimate how bad this problem is and determine weather we need/can address these by adding them to the model.
Questions and Tasks
[ ] What block effects are there?
[ ] What are the explanation for these blocks?
Definition of done
[ ] A list of block effects.
[ ] A set of notes describing the potential causes of block effects.
Story
The S2 RNAi project has a large number of libraries. When dealing with this large number of libraries there are bound to be various block effects. When looking at library size differences between libraries we see various block effects (with in and among plates). I want to estimate how bad this problem is and determine weather we need/can address these by adding them to the model.
Questions and Tasks
Definition of done