Hello, first of all thank you for developing such an important tool.
I have recently tested telomerecat with a lot of WGS at 30x coverage and the results seemed a little strange to me.
First of all, there are a few samples with very short telomere length (e.g. 2186.9) compared to the majority of the other samples (I hope the figure gets uploaded so you can see it). Additionally, the length is not correlated to the length measured by PCR, which is our golden standard. Is there any explanation to these problems?
Hello, first of all thank you for developing such an important tool.
I have recently tested telomerecat with a lot of WGS at 30x coverage and the results seemed a little strange to me. First of all, there are a few samples with very short telomere length (e.g. 2186.9) compared to the majority of the other samples (I hope the figure gets uploaded so you can see it). Additionally, the length is not correlated to the length measured by PCR, which is our golden standard. Is there any explanation to these problems?