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jhuapl-bio / pathogenesis-gene-ontology

An ontology for the functional annotation of genes and gene products involved in pathogenesis
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Elimination or (re)placement of "PATHGO_0000094 Mitogen-activated protein kinase kinases (MAPKKs) protease" #162

Closed genegodbold closed 3 years ago

genegodbold commented 3 years ago

The parent of "PATHGO_0000094 Mitogen-activated protein kinase kinases (MAPKKs) protease" is currently "PATHGO_0000015 Cellular signaling disruption factor" but I suggest that it might be more accurate to place it under "PATHGO_0000288 Host MAPK signaling disruption factor"

For what it's worth, I only know of one MAPKK protease (anthrax lethal factor) while there are over a dozen MAPK signaling disruption factors so you could just drop this ontology entry and it would fit just fine under the latter. In retrospect of the annotation that has been done, it is an oddly specific ontology entry.

Attribution

https://orcid.org/0000-0002-5702-4690

jacakrj1 commented 3 years ago

This term got dropped when the determinant branch was removed so issue is no longer relevant. Agree that it was a highly specific term considering other areas of the ontology.