jhuapl-bio / taxtriage

TaxTriage is a Nextflow workflow designed to agnostically identify and classify microbial organisms within short- or long-read metagenomic NGS data. This flexible tool was developed with various use-cases of mNGS in mind.
MIT License
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RE-implement BLAST refinement strategies #24

Closed Merritt-Brian closed 6 months ago

Merritt-Brian commented 11 months ago

Description of feature

Previously, BLAST was functional at the end of the pipeline (post top hits/re-alignment) but computationally expensive. Consider automated subsampling by hit-type and diversity of sequences for tuning purposes on final reporting metrics.