jinworks / CellChat

R toolkit for inference, visualization and analysis of cell-cell communication from single-cell and spatially resolved transcriptomics
GNU General Public License v3.0
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ligand-receptor interactions in bulk RNA-seq #110

Closed ManarRashad closed 2 months ago

ManarRashad commented 2 months ago

Dears, First of all, thanks a lot for this great package. It helped me a lot in cell-cell communication in scRNA-seq. My question is: I have a bulk array dataset of 406 patients normalized by the LOESS-smoothing algorithm then log transformed. Is there a possibility to apply CellChat to find out the ligand-receptor interaction within this dataset "not cell-cell communication"?

Thanks in advance