jmcbroome / auto-pango-designation

Repository for automated flagging of new lineages for pango designation.
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1279 BA.5.3.1 samples in Germany #162

Closed jmcbroome closed 1 year ago

jmcbroome commented 2 years ago

BA.5.3.1.0 is a proposed sublineage of BA.5.3.1 that includes 1279 samples.

It was identified from the tree file gisaidAndPublic.2022-10-11.proposed.pb as the descendents of node_1873833.

The earliest dated sample was found on 2022-02-19.

The latest dated sample was found on 2022-10-03.

It is found in 49 countries, most commonly Germany where 16.00% of its samples were sequenced.

BA.5.3.1.0 has a Bloom Lab escape score of 0.45, unchanged from the parent lineage.

Full mutational path from the ancestral lineage to the proposed sublineage: T28693C>A27508C>A27749G

Full amino acid change path from the ancestral lineage to the proposed sublineage: >ORF7a:T39P>ORF7a:K119R

NOTE: The following links search by genotype and parent lineage; they may additionally highlight samples outside of the proposed clade that convergently evolved the same mutations or that were added after this lineage was inferred, or not display or highlight samples which reverted some of the key changes or were removed after this lineage was inferred. They may also take a moment to complete the search on loading.

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The following samples are included in this proposal: PAK/68022/2022|OP185171.1|2022-07-04 Germany/BY-RKI-I-955725/2022|EPI_ISL_14692625|2022-08-06 England/QEUH-3ECFF54/2022|OX243019.1|2022-07-06 Germany/SN-RKI-I-947161/2022|EPI_ISL_14432120|2022-07-26 Germany/BW-RKI-I-988935/2022|EPI_ISL_15264122|2022-09-07 USA/CA-HLX-STM-NDV3U3WUR/2022|EPI_ISL_15163331|2022-09-01 SouthKorea/KDCA89701/2022|EPI_ISL_13966789|2022-06-18 USA/1015848824_9-27-2022/2022|OP555037.1|2022-09-21 Japan/TKYkbm39410/2022|EPI_ISL_14718674|2022-07-14 Germany/BE-RKI-I-917639/2022|EPI_ISL_14379047|2022-06-28 Germany/BW-RKI-I-980518/2022|EPI_ISL_15135781|2022-09-10 Germany/BW-RKI-I-900219/2022|EPI_ISL_13934063|2022-07-07 USA/FL-TGH-3862/2022|EPI_ISL_14649672|2022-08-03 Denmark/2022|OX222516.1|2022-06-29 USA/AZ-CDC-LC0870551/2022|OP423793.1|2022-08-29 As well as 1264 additional samples.